Aiming for Fewer Gout Flares
Colchicine is the active ingredient in a medicine called Mitigare®. It has been proven effective in helping prevent flares in adults with gout.1
Adults who took colchicine 0.6 mg daily had fewer gout flares than patients who did not. Adults who took colchicine also had fewer gout flares as time went on.1
43 patients starting allopurinol were randomized to receive cochicine 0.6 mg or placebo for up to 6 months. The chart shows the mean number of acute gout flares at the 0-3 and 3-6 month time periods and overall.
Prophylactic colchicine, in doses of 0.5 to 2.0 mg per day, was given for periods of not less than 2 to no more than 10 years (mean 5.4 years) to 208 gouty subjects selected for analysis because of a prior history of frequent and disabling attacks of acute gouty arthritis.
Colchicine is the active ingredient in Mitigare®. In a 6-month study of patients with recurrent gout, colchicine 0.6 mg was well tolerated.1
- The most common adverse reactions were gastrointestinal symptoms, including diarrhea, nausea, vomiting, and abdominal pain.
- Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Please see Important Safety Information below.
What else can I do to manage my gout flares?
To stay healthy and minimize the impact of gout flares on your life, follow your doctor’s advice and take medicines as prescribed. It may also help to3:
- Drink plenty of non-alcoholic and non-sugary beverages, especially water. These kinds of fluids help remove uric acid from the body.
- Avoid foods containing purines. Foods that are high in purines include red meat, organ meats and certain kinds of seafood.
- Maintain a healthy body weight through diet and exercise.