Is There a Link Between Drinking Coffee and Gout?

coffee and gout

If you start your day with coffee, you’re in good company. According to the results of a survey commissioned by the National Coffee Association, 64 percent of Americans 18 or over drink it every day.1 Everyone knows that coffee is warm, comforting and can help you feel energized, but is there a link between drinking coffee and gout?


Understanding gout

Gout is a type of inflammatory arthritis caused by a build-up of uric acid crystals in the joints and other areas of the body and surrounding tissues.2 Adults with gout can suffer from episodes of pain, redness, swelling and/or extreme tenderness in one or more joints, most commonly the big toe.2


How diet can affect gout

Purines are chemical compounds found in some foods and drinks that the body breaks down into uric acid.2 Generally, the body can process the uric acid that results from purine-rich foods and drinks such as meat, seafood and alcoholic beverages.2 In some people, however, consuming foods and drinks with too many purines can raise the uric acid level and increase the risk of gout and gout flares.2


The potential effect of coffee

While more research is needed, studies suggest that drinking coffee is associated with a lower risk of gout.3,4 One study of more than 45,000 male medical professionals found that the group who drank the most coffee had the lowest risk of gout.3 The risk of gout was 40 percent lower in participants who drank four to five cups of coffee each day, and nearly 60 percent lower in those who drank six or more cups each day.3 The potential benefits of coffee were less pronounced in participants who drank one to three cups per day—these individuals saw just an eight percent reduction in their risk of gout.3

Data from a separate review of a nationally representative sample of American adults (men and women) also suggest that coffee consumption is associated with a lower risk of gout.4 It is not exactly clear why or how drinking coffee may reduce the risk of gout.3,4 However, researchers from both studies agree that coffee is a major source of a strong antioxidant that may affect gout risk.3,4


Gout Friendly Diet Cheat Sheet

Discover the benefits of a gout-friendly diet that may reduce your risk of future flares.

Talk with your doctor

While the potential benefits may be appealing, drinking more coffee may not be healthy for everyone. If you are thinking about changing your morning beverage habits, be sure to first ask your doctor how much coffee is okay for you.


NOTE: This article was not written by a medical professional and is not intended to substitute for the guidance of a physician. These are not Hikma’s recommendations for gout flare prevention, but rather facts and data collected from various reliable medical sources. For a full list of resources and their attributing links, see below.



  1. Americans are drinking a daily cup of coffee at the highest level in six years: survey. Reuters website. Available at: Accessed November 25, 2018.
  2. Gout. Mayo Clinic website. Available at: Accessed 11/25/18.
  3. Choi HK, Willett W, Curhan G. Coffee Consumption and the Risk of Incident Gout in Men: A Prospective Study. Arthritis Rheum. 2007;56(6):2049–2055.
  4. Choi HK, Curhan G. Coffee, tea, and caffeine consumption and serum uric acid level: The third national health and nutrition examination survey. Arthritis Rheum. 2007;57(5):816–821.

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Combining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity. Patients with both renal and hepatic impairment should not be given Mitigare®.
  • Fatal overdoses have been reported with colchicine in adults and children. Keep Mitigare® out of the reach of children.
  • Blood dyscrasias such as myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anemia have been reported with colchicine used in therapeutic doses.
  • Monitor for toxicity and if present consider temporary interruption or discontinuation of colchicine.
  • Drug interaction with dual P-gp and CYP3A4 inhibitors: Co-administration of colchicine with dual P-gp and CYP3A4 inhibitors has resulted in life-threatening interactions and death.
  • Neuromuscular toxicity and rhabdomyolysis may occur with chronic treatment with colchicine in therapeutic doses, especially in combination with other drugs known to cause this effect. Patients with impaired renal function and elderly patients (including those with normal renal and hepatic function) are at increased risk. Consider temporary interruption or discontinuation of Mitigare®.
  • The most commonly reported adverse reactions with colchicine are gastrointestinal symptoms, including diarrhea, nausea, vomiting, and abdominal pain.


Mitigare® is indicated for prophylaxis of gout flares in adults. The safety and effectiveness of Mitigare for acute treatment of gout flares during prophylaxis has not been studied.

Mitigare® is not an analgesic medication and should not be used to treat pain from other causes.

For Full Prescribing Information please CLICK HERE and for Medication Guide CLICK HERE.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit, or call 1-800-FDA-1088.

Manufactured by: West-Ward Columbus Inc., Columbus, OH 43228

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4.