Gender Differences in Gout: What You Need to Know

Gout is a form of inflammatory arthritis that affects about 8 million people in the US.1 You may already know that men are more likely to suffer with the disease than women,1 but it may surprise you to…

More than Just a Swollen Toe—Debunking 6 Common Gout Myths

Gout was first identified by the Egyptians in 2640 BC.1 However, many misconceptions about the disease have developed since then. How much do you know about gout? In this article, we will review some gout myths and reveal some…

I’ve been diagnosed with gout. Now what?

If you have recently learned you have gout, you may have mixed feelings about your diagnosis. Perhaps you are relieved to know that the source of your discomfort is treatable. Or maybe you are worried about how you will manage…

Why Do Gout Attacks Happen at Night?

Many people with gout know what it’s like to be awakened at 3 am with the excruciating pain of a gout flare. But why do gout attacks happen at night? Dr. Hyon Choi, Director of Clinical Epidemiology at Massachusetts General…

How Do I Know if I Have Gout?

If you’ve ever woken up during the night with a burning pain in your foot, you may have had a gout flare.1 But gout can be tricky to diagnose, because its symptoms, when they do appear, are similar to…

Is Gout Hereditary?

Gout is a common form of inflammatory arthritis that is known for its intensely painful attacks.1 Long referred to as “the disease of kings,”2 many people and even some healthcare professionals associate gout with excess—specifically, eating and drinking…

Understanding Gout Flare Triggers

If you’re like a lot of adults with gout, your first experience with the disease was probably very sudden.1 Perhaps you awoke in the middle of the night feeling like your big toe was on fire.1 After spending…

Gout Awareness Day: May 22

Gout Awareness Day, May 22, was created to raise awareness of and educate people about this extremely painful form of inflammatory arthritis.1 Read on to learn more about this common ailment and what you can do to prevent flares.…

The Most Common Gout Symptoms in Adults

Picture this: You’re sound asleep in bed. A few hours ago, you came home from a nice evening out where you had shrimp cocktail, a steak and a glass of wine. All of a sudden, you wake up feeling as…

How Can I Talk to My Doctor About Gout?

Gout, a form of inflammatory arthritis, affects more than eight million Americans.1 The disease is caused by excess uric acid in the bloodstream, a medical condition known as hyperuricemia.1 Adults with gout may experience sudden and severely painful…

How Does Having Gout Affect My Bones and Joint Health?

Gout is a painful form of inflammatory arthritis that is caused by excess uric acid in the bloodstream.1 If you have gout, your doctor may have recommended that you reduce your uric acid level. Reducing your uric acid level…

How Can I Fit Physical Activity Into My Busy Life?

According to the Centers for Disease Control and Prevention, more than 70 percent of American adults are considered overweight or obese.1 Multiple studies show that our increasingly sedentary lifestyles are putting our health at risk.2,3 But finding time…

The Most Common Risk Factors for Gout

Gout is a type of inflammatory arthritis caused by a build-up of uric acid crystals in the bloodstream.1 This condition causes crystals to form and build up around one or more joints.1 People with gout suffer from episodes…

Gout in Women: Not Just a Men’s Disease

Gout is a painful type of inflammatory arthritis that affects more than 8 million people in the US.1 Nearly three times as many men as women have gout.1 However, the risk of gout can increase as a woman…

What Is the Difference Between Gout and Gout Flares?

More than 8 million Americans suffer with gout.1 But many don’t know they have gout because they haven’t experienced gout flares. It’s important to understand the difference between gout and gout flares. Gout, a form of inflammatory arthritis, has…

The Four Stages of Gout: What Could Happen if I Don’t Manage My Gout

If you’ve ever had a gout flare, you know one thing for sure—you never want it to happen again. Flares can occur suddenly, often in the middle of the night.1 You might wake up to find that your big…

How Is Gout Diagnosed in Adults?

Gout is the most common form of inflammatory arthritis, affecting more than one percent of the population.1 However, it can be difficult to accurately diagnose because its symptoms can be similar to those of other diseases.2 To make…

What is Gout?

Gout is a painful form of inflammatory arthritis.1 Approximately 8.3 million Americans live with this disease.1 Gout usually appears first in the big toe, but can also affect the midfoot, ankles, knees, elbows, wrists and hands.2 In…

Top Signs You May Want to See a Doctor for Gout

People with gout, a painful form of inflammatory arthritis, sometimes have an initial occurrence, followed by a long period of time when the gout is in remittance before it flares again.  Eventually, gout flares may occur more frequently and gout…

What Happens to Your Body When You Have Gout?

A frequently asked question is: “What happens to your body when you have gout?” Gout is a type of arthritis. It is caused by the buildup of uric acid crystals in the joints, also called hyperuricemia.1 Gout often occurs…

What You Need to Know After Being Diagnosed with Gout

The big toe often is where gout attacks first. Gout attacks also can occur in the heels, instep, ankles, knees, elbows, hips, thumbs, and fingers. Symptoms of gout include intense pain that often begins in the middle of the night,…

Menopause and Gout: What You Need to Know

Gout, a painful form of inflammatory arthritis, has been in existence since ancient times.1 With its painful swelling and redness, gout often occurs in the big toe and may show up in other body parts, such as in the…

Mitigare® for the Prevention of Gout Flares in Adults: What You Need to Know

Gout is a painful form of inflammatory arthritis1 caused by a condition called hyperuricemia. Hyperuricemia happens when there is too much uric acid in the body. When there is too much uric acid in the body, uric acid crystals…

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Combining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity. Patients with both renal and hepatic impairment should not be given Mitigare®.
  • Fatal overdoses have been reported with colchicine in adults and children. Keep Mitigare® out of the reach of children.
  • Blood dyscrasias such as myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anemia have been reported with colchicine used in therapeutic doses.
  • Monitor for toxicity and if present consider temporary interruption or discontinuation of colchicine.
  • Drug interaction with dual P-gp and CYP3A4 inhibitors: Co-administration of colchicine with dual P-gp and CYP3A4 inhibitors has resulted in life-threatening interactions and death.
  • Neuromuscular toxicity and rhabdomyolysis may occur with chronic treatment with colchicine in therapeutic doses, especially in combination with other drugs known to cause this effect. Patients with impaired renal function and elderly patients (including those with normal renal and hepatic function) are at increased risk. Consider temporary interruption or discontinuation of Mitigare®.
  • The most commonly reported adverse reactions with colchicine are gastrointestinal symptoms, including diarrhea, nausea, vomiting, and abdominal pain.

Indication

Mitigare® is indicated for prophylaxis of gout flares in adults. The safety and effectiveness of Mitigare for acute treatment of gout flares during prophylaxis has not been studied.

Mitigare® is not an analgesic medication and should not be used to treat pain from other causes.

For Full Prescribing Information please CLICK HERE and for Medication Guide CLICK HERE.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Manufactured by: West-Ward Columbus Inc., Columbus, OH 43228

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Combining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity. Patients with both renal and hepatic impairment should not be given Mitigare®.
  • Fatal overdoses have been reported with colchicine in adults and children. Keep Mitigare® out of the reach of children.