How Does Having Gout Affect My Bones and Joint Health?

Gout is a painful form of inflammatory arthritis that is caused by excess uric acid in the bloodstream.1 If you have gout, your doctor may have recommended that you reduce Read more...

The Most Common Risk Factors for Gout

Gout is a type of inflammatory arthritis caused by a build-up of uric acid crystals in the bloodstream.1 This condition causes crystals to form and build up around one or more Read more...

Gout Management Costs & Why Prevention Matters

Gout is becoming increasingly common in the US.1 About 6 million men and 2 million women in the US suffer with it2, and incidence of the disease has more than Read more...

Gout in Women: Not Just a Men’s Disease

Gout is a painful type of inflammatory arthritis that affects more than 8 million people in the US.1 Nearly three times as many men as women have gout.1 However, the Read more...

What Is the Difference Between Gout and Gout Flares?

More than 8 million Americans suffer with gout.1 But many don’t know they have gout because they haven’t experienced gout flares. It’s important to understand the difference between gout and gout Read more...

The Four Stages of Gout: What Could Happen if I Don’t Manage My Gout

If you’ve ever had a gout flare, you know one thing for sure—you never want it to happen again. Flares can occur suddenly, often in the middle of the night.1 Read more...

Understanding Gout: A Glossary of Commonly Used Gout Terms

Here are some of the terms often used to describe gout, gout flares and gout prevention.   Commonly Used Gout Terms acute gouty arthritis—A condition where uric acid crystals form Read more...

3 Things You Should Know About Generic Colchicine 0.6 mg Capsules

Colchicine is a medicine used to help prevent gout flares in adults.1 Gout is a form of inflammatory arthritis that occurs when too much uric acid builds up in the Read more...

Consider Mitigare® (colchicine) 0.6 mg Capsules for Preventing Gout Flares in Adults

Gout is a type of inflammatory arthritis caused by a condition called hyperuricemia.1 Hyperuricemia happens when there is too much uric acid in the body.1 When hyperuricemia becomes severe, uric Read more...

What is Gout?

Gout is a painful form of inflammatory arthritis.1 Approximately 8.3 million Americans live with this disease.1 Gout usually appears first in the big toe, but can also affect the midfoot, Read more...

What Men Need to Know About Gout

Gout, a painful form of inflammatory arthritis, causes swelling and redness in the big toe and feet, as well as other body parts.1 Gout results from an overproduction by the body Read more...

What Happens to Your Body When You Have Gout?

A frequently asked question is: “What happens to your body when you have gout?” Gout is a type of arthritis. It is caused by the buildup of uric acid crystals Read more...

What You Need to Know After Being Diagnosed with Gout

The big toe often is where gout attacks first. Gout attacks also can occur in the heels, instep, ankles, knees, elbows, hips, thumbs, and fingers. Symptoms of gout include intense Read more...

Couples and Gout: What You Need to Know

Gout is a form of inflammatory arthritis. Unlike other types of arthritis, it’s caused by a build-up of uric acid in the body. This build-up of uric acid can lead to Read more...

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Combining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity. Patients with both renal and hepatic impairment should not be given Mitigare®.
  • Fatal overdoses have been reported with colchicine in adults and children. Keep Mitigare® out of the reach of children.
  • Blood dyscrasias such as myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anemia have been reported with colchicine used in therapeutic doses.
  • Monitor for toxicity and if present consider temporary interruption or discontinuation of colchicine.
  • Drug interaction with dual P-gp and CYP3A4 inhibitors: Co-administration of colchicine with dual P-gp and CYP3A4 inhibitors has resulted in life-threatening interactions and death.
  • Neuromuscular toxicity and rhabdomyolysis may occur with chronic treatment with colchicine in therapeutic doses, especially in combination with other drugs known to cause this effect. Patients with impaired renal function and elderly patients (including those with normal renal and hepatic function) are at increased risk. Consider temporary interruption or discontinuation of Mitigare®.
  • The most commonly reported adverse reactions with colchicine are gastrointestinal symptoms, including diarrhea, nausea, vomiting, and abdominal pain.

Indication

Mitigare® is indicated for prophylaxis of gout flares in adults. The safety and effectiveness of Mitigare for acute treatment of gout flares during prophylaxis has not been studied.

Mitigare® is not an analgesic medication and should not be used to treat pain from other causes.

For Full Prescribing Information please CLICK HERE and for Medication Guide CLICK HERE.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Manufactured by: West-Ward Columbus Inc., Columbus, OH 43228

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Combining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity. Patients with both renal and hepatic impairment should not be given Mitigare®.
  • Fatal overdoses have been reported with colchicine in adults and children. Keep Mitigare® out of the reach of children.