The Risks of Uncontrolled Gout

Anyone who has ever had a gout flare knows how excruciating the condition can be.1 However, the agony of gout isn’t necessarily the most significant concern associated with the disease.2 In addition to painful attacks, the risks of…

What is the Relationship Between Gout and Kidney Disease?

People who suffer with gout are more likely to develop kidney disease.1 Similarly, those with kidney disease are more liable to have elevated uric acid levels and suffer with gout.1 But knowing there could be a connection may…

Answers to Questions About Gout You May Be Afraid to Ask

Gout is the most common inflammatory arthritis in the US and acute gout flares are among the most painful events humans can experience.1 Yet, many people who suffer with it don’t ask questions when they see the doctor. Read…

How Might the Stress of COVID-19 Affect Gout?

For many people, the outbreak of coronavirus (COVID-19) is a major source of fear and anxiety.1 If you have gout, the extra stress you may be feeling could affect you in ways you might not expect.2,3 Some folks…

Gout Awareness Day: May 22

Gout Awareness Day, May 22, was created to raise awareness of and educate people about this extremely painful form of inflammatory arthritis.1 Read on to learn more about this common ailment and what you can do to prevent flares.…

Gout Quiz—Test Your Knowledge of Gout

How much do you know about gout? Take this interesting and informative gout quiz and test your knowledge. TAKE QUIZ…

A Brief History of Gout Disease

First identified by the Egyptians around 2640 BC, gout is one of the earliest known diseases.1 Millions of people (mostly men) still suffer with it today.2 Fortunately, scientists have learned a lot about this potentially debilitating condition over…

2020 Update to Gout Management Guidelines

The American College of Rheumatology (ACR) is a non-profit, global organization committed to improving the care of people with rheumatic diseases, including gout.1 To establish the most effective disease management strategies and ensure the best outcomes for patients, the…

How to Track Your Gout Triggers and Gout Attacks

Gout attacks, or flares, can be caused by a number of triggers.1-3 Although some of them are outside of your control, others may be avoidable.1-3 Keeping track of your gout attacks and the circumstances that surround them may…

Serum Uric Acid and Other Important Numbers for People With Gout

You may have heard that gout is caused by excess uric acid in your bloodstream, a condition known as hyperuricemia.1 But did you know that having excess uric acid in your bloodstream can increase your risk of other health…

How to Handle a Gout Attack

For many people with gout, it’s hard to imagine anything more painful than a gout attack.1 Fortunately, there are a number of ways you can ease the intense pain, heat and swelling associated with one of these episodes, as…

Don’t Let Gout Get You Down—Get the Gout Treatment You Need and Deserve

Gout is a common form of inflammatory arthritis that affects more than 8 million Americans.1 Unfortunately, fewer than one in three people who have it are getting the gout treatment they need.2 If you have gout, it is…

Gender Differences in Gout: What You Need to Know

Gout is a form of inflammatory arthritis that affects about 8 million people in the US.1 You may already know that men are more likely to suffer with the disease than women,1 but it may surprise you to…

More than Just a Swollen Toe—Debunking 6 Common Gout Myths

Gout was first identified by the Egyptians in 2640 BC.1 However, many misconceptions about the disease have developed since then. How much do you know about gout? In this article, we will review some gout myths and reveal some…

Frequently Asked Questions About Gout

Learning everything you can about gout may help you to feel more in control of the disease and make more informed decisions about your care. Read on to get the answers to some frequently asked questions about gout.   What…

I’ve been diagnosed with gout. Now what?

If you have recently learned you have gout, you may have mixed feelings about your diagnosis. Perhaps you are relieved to know that the source of your discomfort is treatable. Or maybe you are worried about how you will manage…

Why Do Gout Attacks Happen at Night?

Many people with gout know what it’s like to be awakened at 3 am with the excruciating pain of a gout flare. But why do gout attacks happen at night? Dr. Hyon Choi, Director of Clinical Epidemiology at Massachusetts General…

How Do I Know if I Have Gout?

If you’ve ever woken up during the night with a burning pain in your foot, you may have had a gout flare.1 But gout can be tricky to diagnose, because its symptoms, when they do appear, are similar to…

Is Gout Hereditary?

Gout is a common form of inflammatory arthritis that is known for its intensely painful attacks.1 Long referred to as “the disease of kings,”2 many people and even some healthcare professionals associate gout with excess—specifically, eating and drinking…

The Most Common Gout Symptoms in Adults

Picture this: You’re sound asleep in bed. A few hours ago, you came home from a nice evening out where you had shrimp cocktail, a steak and a glass of wine. All of a sudden, you wake up feeling as…

How Can I Talk to My Doctor About Gout?

Gout, a form of inflammatory arthritis, affects more than eight million Americans.1 The disease is caused by excess uric acid in the bloodstream, a medical condition known as hyperuricemia.1 Adults with gout may experience sudden and severely painful…

How Does Having Gout Affect My Bones and Joint Health?

Gout is a painful form of inflammatory arthritis that is caused by excess uric acid in the bloodstream.1 If you have gout, your doctor may have recommended that you reduce your uric acid level. Reducing your uric acid level…

The Most Common Risk Factors for Gout

Gout is a type of inflammatory arthritis caused by a build-up of uric acid crystals in the bloodstream.1 This condition causes crystals to form and build up around one or more joints.1 People with gout suffer from episodes…

Gout Management Costs & Why Prevention Matters

Gout is becoming increasingly common in the US.1 About 6 million men and 2 million women in the US suffer with it2, and incidence of the disease has more than doubled over the past 20 years1

Gout in Women: Not Just a Men’s Disease

Gout is a painful type of inflammatory arthritis that affects more than 8 million people in the US.1 Nearly three times as many men as women have gout.1 However, the risk of gout can increase as a woman…

What Is the Difference Between Gout and Gout Flares?

More than 8 million Americans suffer with gout.1 But many don’t know they have gout because they haven’t experienced gout flares. It’s important to understand the difference between gout and gout flares. Gout, a form of inflammatory arthritis, has…

The Four Stages of Gout: What Could Happen if I Don’t Manage My Gout

If you’ve ever had a gout flare, you know one thing for sure—you never want it to happen again. Flares can occur suddenly, often in the middle of the night.1 You might wake up to find that your big…

Understanding Gout: A Glossary of Commonly Used Gout Terms

Here are some of the terms often used to describe gout, gout flares and gout prevention.   Commonly Used Gout Terms acute gouty arthritis—A condition where uric acid crystals form in the joints causing sudden and intense pain, swelling and…

3 Things You Should Know About Generic Colchicine 0.6 mg Capsules

Colchicine is a medicine used to help prevent gout flares in adults.1 Gout is a form of inflammatory arthritis that occurs when too much uric acid builds up in the joints, leading to chronic swelling and often intense pain.…

Consider Mitigare® (colchicine) 0.6 mg Capsules for Preventing Gout Flares in Adults

Gout is a type of inflammatory arthritis caused by a condition called hyperuricemia.1 Hyperuricemia happens when there is too much uric acid in the body.1 When hyperuricemia becomes severe, uric acid crystals can build up in the joints,…

What is Gout?

Gout is a painful form of inflammatory arthritis.1 Approximately 8.3 million Americans live with this disease.1 Gout usually appears first in the big toe, but can also affect the midfoot, ankles, knees, elbows, wrists and hands.2 In…

What Men Need to Know About Gout

Gout, a painful form of inflammatory arthritis, causes swelling and redness in the big toe and feet, as well as other body parts.1 Gout results from an overproduction by the body of uric acid, which can build up in…

What Happens to Your Body When You Have Gout?

A frequently asked question is: “What happens to your body when you have gout?” Gout is a type of arthritis. It is caused by the buildup of uric acid crystals in the joints, also called hyperuricemia.1 Gout often occurs…

What You Need to Know After Being Diagnosed with Gout

The big toe often is where gout attacks first. Gout attacks also can occur in the heels, instep, ankles, knees, elbows, hips, thumbs, and fingers. Symptoms of gout include intense pain that often begins in the middle of the night,…

Couples and Gout: What You Need to Know

Gout is a form of inflammatory arthritis. Unlike other types of arthritis, it’s caused by a build-up of uric acid in the body. This build-up of uric acid can lead to deposits of crystals that form around the joints, often…

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Combining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity. Patients with both renal and hepatic impairment should not be given Mitigare®.
  • Fatal overdoses have been reported with colchicine in adults and children. Keep Mitigare® out of the reach of children.
  • Blood dyscrasias such as myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anemia have been reported with colchicine used in therapeutic doses.
  • Monitor for toxicity and if present consider temporary interruption or discontinuation of colchicine.
  • Drug interaction with dual P-gp and CYP3A4 inhibitors: Co-administration of colchicine with dual P-gp and CYP3A4 inhibitors has resulted in life-threatening interactions and death.
  • Neuromuscular toxicity and rhabdomyolysis may occur with chronic treatment with colchicine in therapeutic doses, especially in combination with other drugs known to cause this effect. Patients with impaired renal function and elderly patients (including those with normal renal and hepatic function) are at increased risk. Consider temporary interruption or discontinuation of Mitigare®.
  • The most commonly reported adverse reactions with colchicine are gastrointestinal symptoms, including diarrhea, nausea, vomiting, and abdominal pain.

Indication

Mitigare® is indicated for prophylaxis of gout flares in adults. The safety and effectiveness of Mitigare for acute treatment of gout flares during prophylaxis has not been studied.

Mitigare® is not an analgesic medication and should not be used to treat pain from other causes.

For Full Prescribing Information please CLICK HERE and for Medication Guide CLICK HERE.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Manufactured by: West-Ward Columbus Inc., Columbus, OH 43228

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4.