Colchicine Savings Program to End 12/31/23

Mitigare® True Blue Savings Program Ends This Month West-Ward Pharmaceuticals Inc. (now Hikma Pharmaceuticals USA Inc.) changed the Colchicine market in 2016 by introducing Mitigare® (Colchicine) 0.6mg Capsules for prophylaxis of gout flares in adults.1 Soon after…

3 Things You Should Know About Generic Colchicine 0.6 mg Capsules, 2022 Update

Gout is a common form of arthritis that affects more than nine million Americans.1 The root cause of the condition is excess uric acid in the bloodstream.1 When the uric acid level in the body remains high for

Protecting Your Joints as You Age With Gout

Whether you’re 30 or 80, you know that certain aspects of the aging process are inevitable. But it’s not a hopeless situation—there are things you can do to preserve your quality of life as you get older.1 Maintaining your…

3 Reasons to Choose the Colchicine Capsule

Many people take colchicine to help prevent the sudden, painful episodes known as gout flares (also known as gout attacks).1,2 The drug is available in capsule, tablet and liquid formulations.3 Some people may find that Colchicine Capsules have

Summer Shoes for Gout: What Should I Look for if I Have Gout in My Feet?

Ah, summer. Finally time to put away the heavy coats and trade in boots for summer kicks. But what are the best summer shoes for gout? And what should you look for in a summer shoe if you have gout…

Should I Take Allopurinol or Colchicine to Prevent Gout Attacks?

If you have gout, your friends and family members probably try to give you all kinds of advice: “Drink more water.” “Stay away from red meat and shellfish.” “Get some exercise.” But what about medication? Some people might want to…

Gout Awareness Day: May 22

Gout Awareness Day, May 22, was created to raise awareness of and educate people about this extremely painful form of inflammatory arthritis.1 Read on to learn more about this common ailment and what you can do to prevent flares.…

The Risks of Uncontrolled Gout

Anyone who has ever had a gout flare knows how excruciating the condition can be.1 However, the agony of gout isn’t necessarily the most significant concern associated with the disease.2 In addition to painful attacks, the risks of…

Taking Colchicine With ULT

If you have gout, chances are your doctor has prescribed urate-lowering therapy (ULT) to reduce the amount of uric acid in your bloodstream and help manage the disease.1 But did you know that you might also need to take…

Answers to Questions About Gout You May Be Afraid to Ask

Gout is the most common inflammatory arthritis in the US and acute gout flares are among the most painful events humans can experience.1 Yet, many people who suffer with it don’t ask questions when they see the doctor. Read…

The Cost of Colchicine

As you’re probably aware, prescription drug prices in the US have been creeping up for years.1 Some have been rising more quickly than others, however.1 The price of Colcrys® (colchicine, USP) tablets, for example, has increased by…

A Brief History of Gout Disease

First identified by the Egyptians around 2640 BC, gout is one of the earliest known diseases.1 Millions of people (mostly men) still suffer with it today.2 Fortunately, scientists have learned a lot about this potentially debilitating condition over…

Is There a Way to Save on Colchicine?

If you take a urate-lowering therapy (ULT) for gout, you may also take one of these colchicine products to help prevent gout flares: Mitigare® (Colchicine) 0.6 mg Capsules Authorized Generic Colchicine 0.6 mg Capsules Colcrys (colchicine, USP) 0.6 mg…

More than Just a Swollen Toe—Debunking 6 Common Gout Myths

Gout was first identified by the Egyptians in 2640 BC.1 However, many misconceptions about the disease have developed since then. How much do you know about gout? In this article, we will review some gout myths and reveal some…

How Do I Know if I Have Gout?

If you’ve ever woken up during the night with a burning pain in your foot, you may have had a gout flare.1 But gout can be tricky to diagnose, because its symptoms, when they do appear, are similar to…

Understanding Gout Flare Triggers

If you’re like a lot of adults with gout, your first experience with the disease was probably very sudden.1 Perhaps you awoke in the middle of the night feeling like your big toe was on fire.1 After spending…

Generic vs Brand-name Drugs

Perhaps you’ve come home from a recent trip to the drugstore to find that your prescription for a brand-name drug has been filled with a generic version. But do generic medicines work the same as branded medicines? According to the…

Allopurinol and Colchicine May Help Adults Prevent Gout Flares

More than eight million Americans are currently living with gout.1 If you are one of them, your doctor may have prescribed you a urate-lowering therapy (ULT) such as allopurinol. Allopurinol can help to prevent gout flares because it slows…

Which Medications May Interact With Mitigare®?

Any time you start on a new medication, it is important to consider how it might interact with the other medicines, vitamins or supplements you are already taking. What are some medications that may interact with Mitigare®? Read…

Why Is the Color of a Medication Important?

According to the US Food and Drug Administration, medication errors are the most common type of mistake made in health care.1 However, the color of a medication can reduce the risk of these errors by helping patients confirm that…

Consider Mitigare® (colchicine) 0.6 mg Capsules for Preventing Gout Flares in Adults

Gout is a type of inflammatory arthritis caused by a condition called hyperuricemia.1 Hyperuricemia happens when there is too much uric acid in the body.1 When hyperuricemia becomes severe, uric acid crystals can build up in the joints,…

Top Signs You May Want to See a Doctor for Gout

People with gout, a painful form of inflammatory arthritis, sometimes have an initial occurrence, followed by a long period of time when the gout is in remittance before it flares again.  Eventually, gout flares may occur more frequently and gout…

Colchicine: How Does It Help Adults with Gout?

Gout is a type of arthritis caused by a build-up of uric acid crystals in the joints and other areas of the body and surrounding tissues. These crystals come from the body’s breakdown of purines, which occur naturally in your…

Mitigare® for the Prevention of Gout Flares in Adults: What You Need to Know

Gout is a painful form of inflammatory arthritis1 caused by a condition called hyperuricemia. Hyperuricemia happens when there is too much uric acid in the body. When there is too much uric acid in the body, uric acid crystals…

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4. Combining these dual inhibitors with colchicine in patients with renal or hepatic impairment has resulted in life-threatening or fatal colchicine toxicity. Patients with both renal and hepatic impairment should not be given Mitigare®.
  • Fatal overdoses have been reported with colchicine in adults and children. Keep Mitigare® out of the reach of children.
  • Blood dyscrasias such as myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anemia have been reported with colchicine used in therapeutic doses.
  • Monitor for toxicity and if present consider temporary interruption or discontinuation of colchicine.
  • Drug interaction with dual P-gp and CYP3A4 inhibitors: Co-administration of colchicine with dual P-gp and CYP3A4 inhibitors has resulted in life-threatening interactions and death.
  • Neuromuscular toxicity and rhabdomyolysis may occur with chronic treatment with colchicine in therapeutic doses, especially in combination with other drugs known to cause this effect. Patients with impaired renal function and elderly patients (including those with normal renal and hepatic function) are at increased risk. Consider temporary interruption or discontinuation of Mitigare®.
  • The most commonly reported adverse reactions with colchicine are gastrointestinal symptoms, including diarrhea, nausea, vomiting, and abdominal pain.

Indication

Mitigare® is indicated for prophylaxis of gout flares in adults. The safety and effectiveness of Mitigare for acute treatment of gout flares during prophylaxis has not been studied.

Mitigare® is not an analgesic medication and should not be used to treat pain from other causes.

For Full Prescribing Information please CLICK HERE and for Medication Guide CLICK HERE.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Manufactured by: West-Ward Columbus Inc., Columbus, OH 43228

Important Safety Information for Mitigare® (colchicine) 0.6 mg capsules

  • Colchicine 0.6 mg capsules are contraindicated in patients with renal or hepatic impairment who are currently prescribed drugs that inhibit both P-gp and CYP3A4.